Developed in Heidelberg, Germany

Standardized CAR-T Detection Reagents for Global Flow Cytometry

  • Batch-to-batch consistent
  • Engineered for high precision
  • Very low background
  • Optional receptor density quantification

Turning fragmented CAR-T flow cytometry workflows into standardized, comparable measurements.

Precision Detection
for CAR-T Monitoring

Enabling standardized cell therapy measurements

How It Works

Quantitative CAR-T Measurement Principle

From engineered antigen binding to reproducible CAR expression readouts.

01

High-Specificity CAR Binding

Engineered antigen-based detection reagents are designed to bind CAR-specific structures with high sensitivity and specificity.

02

Very Low Background

Optimized Fc-region design and reagent configuration help reduce non-specific binding and improve signal clarity.

03

Batch-to-Batch Consistency

Controlled manufacturing, strict quality control, and site-specific fluorochrome conjugation support consistent reagent performance across batches.

04

Optional Receptor Density Quantification

SCOPE Cell Mimics support quantitative receptor-density readouts, including Accessible CAR Molecules per cell.

2,000+

CAR-T cell samples analyzed

Supporting robust assay development and validation.

Why Today's CAR-T Monitoring Falls Short

Current CAR-T flow cytometry workflows often force laboratories to choose between high-quality but expensive detection reagents, or lower-cost alternatives with limited validation, variable performance, and reduced comparability.

Current Market Status
BlueRay Precision Standard

High cost per test

Premium detection reagents can limit routine monitoring and large-scale use.

Affordable per-test workflow

Designed to support broader use across research groups and industry partners.

Batch-to-batch variability

Lot-dependent differences, including fluorochrome configuration and labeling variation, can affect staining consistency.

Batch-consistent reagents

Controlled production, strict quality control, and defined fluorochrome conjugation ratios support reproducible staining performance.

Local lab-dependent protocols

Different gates, reagent formats, and workflows make results difficult to compare between sites.

Simplified one-step staining

Designed for standardized CAR-T measurement workflows with comparable readouts across laboratories and instruments.

Limited quantitative calibration

Many workflows report CAR-positive percentages without standardized receptor-density information.

Optional ACM readout

Supports CAR-positive percentage measurement and optional receptor density quantification as Accessible CAR Molecules per cell.

From fragmented CAR-T monitoring to standardized quantitative flow cytometry.

Products

Featured Detection Reagents

Ready-to-use reagents for CAR-T cell detection

CD19 Detection Reagent

CD19 Detection Reagent

Antigen-based detection reagent for CD19 CAR T cells with high specificity and reproducibility.

BCMA Detection Reagent

BCMA Detection Reagent

Optimized detection reagent for BCMA CAR T cells, enabling precise monitoring workflows.

Technology

The SCOPE Technology Platform

A comprehensive approach to standardized CAR T cell detection and quantification

SCOPE Detection Reagents

Antigen-based CAR detection reagents optimized for stable, reproducible staining, low background, and high specificity.

Learn more

SCOPE Reference Cell Mimics

Standardized reference materials designed to support assay consistency, workflow checks, and inter-lab comparability.

Learn more

SCOPE Certification

Coming soon: proficiency-style support for external quality assessment and consistent reporting.

Join early access

Why Choose Us

Technical Advantages

Low Background & High Specificity

Robust performance with minimal non-specific binding.

Manufacturing Reproducibility

Optimized processes ensure batch-to-batch consistency.

Universal Flow Cytometry Compatibility

Works with standard flow cytometry platforms and workflows.

Quantitative CAR-T Monitoring

Supports CAR-positive percentage and optional ACM readouts.

Need Consistent CAR-T Monitoring Across Sites?

Contact our team to discuss how SCOPE reagents can support reproducible CAR-T cell monitoring across sites.